Difloxacin Hydrochloride Salt

• CAT Number: R004278
• CAS Number: 91296-86-5
• Molecular Formula: C21H20ClF2N3O3
• Molecular Weight: 435.85
• Purity: ≥95%
• Synonyms: 6-Fluoro-1-(4-fluorophenyl)-1,4-dihydro-7-(4-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic Acid Hydrochloride Salt
• Target: Bacterial
• Storage: Store at -20°C
• IUPAC Name: 6-fluoro-1-(4-fluorophenyl)-7-(4-methylpiperazin-1-yl)-4-oxoquinoline-3-carboxylic acid;hydrochloride
• InChI: InChI=1S/C21H19F2N3O3.ClH/c1-24-6-8-25(9-7-24)19-11-18-15(10-17(19)23)20(27)16(21(28)29)12-26(18)14-4-2-13(22)3-5-14;/h2-5,10-12H,6-9H2,1H3,(H,28,29);1H
• InChIKey: JFMGBGLSDVIOHL-UHFFFAOYSA-N
• SMILES: CN1CCN(CC1)C2=C(C=C3C(=C2)N(C=C(C3=O)C(=O)O)C4=CC=C(C=C4)F)F.Cl

Difloxacin Hydrochloride Salt（Cat No.:R004278）is a high-purity antibiotic compound, primarily used in pharmaceutical research for studying bacterial infections and their resistance mechanisms. This compound is a hydrochloride salt form of difloxacin, a fluoroquinolone antibiotic known for its potent antibacterial activity. It is effective against a broad spectrum of Gram-negative and Gram-positive bacteria by inhibiting DNA gyrase and topoisomerase IV, enzymes critical for bacterial DNA replication. Difloxacin Hydrochloride Salt is valuable for research into new antimicrobial therapies and for examining the pharmacokinetics and efficacy of fluoroquinolones in drug development.

Reference

Wolfson, John S., and David C. Hooper. /The Fluoroquinolones: Structures, Mechanisms of Action and Resistance, and Spectra of Activity in Vitro./ American Society for Microbiology 4th ser. 28 (1985): 581-86.