Diflunisal

• CAT Number: A000051
• CAS Number: 22494-42-4
• Molecular Formula: C13H8F2O3
• Molecular Weight: 250.201
• Purity: ≥95%
• Synonyms: Dolobid, Dolobis, Flovacil, Fluniget
• Target: COX
• Solubility: Soluble in DMSO
• Storage: Store at -20°C
• IUPAC Name: 5-(2,4-difluorophenyl)-2-hydroxybenzoic acid
• InChI: InChI=1S/C13H8F2O3/c14-8-2-3-9(11(15)6-8)7-1-4-12(16)10(5-7)13(17)18/h1-6,16H,(H,17,18)
• InChIKey: HUPFGZXOMWLGNK-UHFFFAOYSA-N
• SMILES: C1=CC(=C(C=C1C2=C(C=C(C=C2)F)F)C(=O)O)O

Diflunisal is a salicylic acid derivative with analgesic and anti-inflammatory activity. It was developed by Merck Sharp & Dohme in 1971 after showing promise in a research project studying more potent chemical analogs of aspirin. It was first sold under the brand name Dolobid, marketed by Merck & Co., but generic versions are now widely available. It is classed as a non-steroidal anti-inflammatory drug (NSAID).

Reference

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