For research use only. Not for therapeutic Use.
Digallic acid is a natural polyphenolic that can be produced by hydrolysis of gallotannins. Like other polyphenolic compounds, digallic acid has antioxidant activity that can be cytoprotective. Digallic acid inhibits reverse transcriptases from human immunodeficiency virus (K<sub>i</sub> = 0.58 µM) and murine leukemia virus. It also inhibits calcium-activated chloride channels, blocking the initial agonist-stimulated chloride current.
| Catalog Number | R066942 |
| CAS Number | 536-08-3 |
| Synonyms | m-Galloylgallic acid;NSC 59263 |
| Molecular Formula | C14H10O9 |
| Purity | ≥95% |
| Storage | -20°C |
| IUPAC Name | 3,4-dihydroxy-5-(3,4,5-trihydroxybenzoyl)oxybenzoic acid |
| InChI | InChI=1S/C14H10O9/c15-7-2-6(3-8(16)11(7)18)14(22)23-10-4-5(13(20)21)1-9(17)12(10)19/h1-4,15-19H,(H,20,21) |
| InChIKey | COVFEVWNJUOYRL-UHFFFAOYSA-N |
| SMILES | C1=C(C=C(C(=C1O)O)O)C(=O)OC2=CC(=CC(=C2O)O)C(=O)O |
| Reference | 1.Bhouri, W.,Derbel, S.,Skandrani, I., et al. Study of genotoxic, antigenotoxic and antioxidant activities of the digallic acid isolated from Pistacia lentiscus fruits. Toxicol. In Vitro 24(2), 509-515 (2010). |
