For research use only. Not for therapeutic Use.
A potent, full efficacy dopamine D<sub>1</sub> agonist which shows no agonist activity at peripheral D<sub>2</sub> receptors or adrenoceptors at doses which cause maximal stimulation of D<sub>1</sub> sites. The compound appears to be fully bioavailable in brain and exhibits profound antiparkinsonism effects <em>in vivo</em>.
Catalog Number | I010317 |
CAS Number | 158704-02-0 |
Synonyms | (±)-trans-10,11-Dihydroxy-5,6,6a,7,8,12b-hexahydrobenzo[a]phenanthridine hydrochloride |
Molecular Formula | C17H18ClNO2 |
Purity | ≥95% |
Target | Dopamine Receptor |
Solubility | Soluble to 10 mM in water and to 50 mM in DMSO |
Storage | Desiccate at +4C |
IUPAC Name | (6aR,12bS)-5,6,6a,7,8,12b-hexahydrobenzo[a]phenanthridine-10,11-diol;hydrochloride |
InChI | InChI=1S/C17H17NO2.ClH/c19-15-7-10-5-6-14-17(13(10)8-16(15)20)12-4-2-1-3-11(12)9-18-14;/h1-4,7-8,14,17-20H,5-6,9H2;1H/t14-,17-;/m1./s1 |
InChIKey | IJYUPBNUPIRQEP-SATBOSKTSA-N |
SMILES | C1CC2=CC(=C(C=C2C3C1NCC4=CC=CC=C34)O)O.Cl |