Dihydrexidine hydrochloride

• CAT Number: I010317
• CAS Number: 158704-02-0
• Molecular Formula: C17H18ClNO2
• Molecular Weight: 303.79
• Purity: ≥95%
• Synonyms: (±)-trans-10,11-Dihydroxy-5,6,6a,7,8,12b-hexahydrobenzo[a]phenanthridine hydrochloride
• Target: Neuronal Signaling
• Solubility: Soluble to 10 mM in water and to 50 mM in DMSO
• Storage: Desiccate at +4C
• IUPAC Name: (6aR,12bS)-5,6,6a,7,8,12b-hexahydrobenzo[a]phenanthridine-10,11-diol;hydrochloride
• InChI: InChI=1S/C17H17NO2.ClH/c19-15-7-10-5-6-14-17(13(10)8-16(15)20)12-4-2-1-3-11(12)9-18-14;/h1-4,7-8,14,17-20H,5-6,9H2;1H/t14-,17-;/m1./s1
• InChIKey: IJYUPBNUPIRQEP-SATBOSKTSA-N
• SMILES: C1CC2=CC(=C(C=C2[C@@H]3[C@@H]1NCC4=CC=CC=C34)O)O.Cl

Dihydrexidine hydrochloride（Cat No.:I010317）is a selective dopamine D1 receptor agonist, primarily studied for its potential therapeutic applications in neurological disorders, including Parkinson’s disease. It works by stimulating D1 receptors in the brain, which play a key role in regulating motor control and cognitive function. Dihydrexidine has shown promise in preclinical studies for improving motor symptoms and cognitive performance by enhancing dopaminergic signaling. It is considered a potential alternative to traditional dopamine therapies, with the aim to provide more targeted and effective treatment options for Parkinson’s disease and other neurodegenerative conditions.