For research use only. Not for therapeutic Use.
Dihydro Dutasteride(CAT: R057039) is a metabolite of dutasteride with significant pharmaceutical relevance. Dutasteride is employed in treating benign prostatic hyperplasia (BPH) and male pattern baldness. Dihydro Dutasteride is formed in the body as a breakdown product of dutasteride and contributes to its pharmacological effects. This compound inhibits 5-alpha-reductase enzymes, which convert testosterone to dihydrotestosterone (DHT). By doing so, it helps reduce prostate gland enlargement in BPH and promotes hair growth in androgenetic alopecia.
Catalog Number | R057039 |
CAS Number | 164656-22-8 |
Synonyms | (4aR,4bS,6aS,7S,9aS,9bS,11aR)-N-[2,5-Bis(trifluoromethyl)phenyl]hexadecahydro-4a,6a-dimethyl-2-oxo-1H-Indeno[5,4-f]quinoline-7-carboxamide; (5α,17β)-N-[2,5-Bis?(trifluoromethyl)phenyl]-3-oxo-4-azaandrostane-17-carboxamide; Dihydrodutasteride; |
Molecular Formula | C27H32F6N2O2 |
Purity | ≥95% |
Target | Drug Metabolite |
Storage | -20°C |
IUPAC Name | (1S,3aS,3bS,5aR,9aR,9bS,11aS)-N-[2,5-bis(trifluoromethyl)phenyl]-9a,11a-dimethyl-7-oxo-1,2,3,3a,3b,4,5,5a,6,8,9,9b,10,11-tetradecahydroindeno[5,4-f]quinoline-1-carboxamide |
InChI | InChI=1S/C27H32F6N2O2/c1-24-11-9-17-15(4-8-21-25(17,2)12-10-22(36)35-21)16(24)6-7-19(24)23(37)34-20-13-14(26(28,29)30)3-5-18(20)27(31,32)33/h3,5,13,15-17,19,21H,4,6-12H2,1-2H3,(H,34,37)(H,35,36)/t15-,16-,17-,19+,21+,24-,25+/m0/s1 |
InChIKey | AIUHDIPAGREENV-QWBYCMEYSA-N |
SMILES | CC12CCC3C(C1CCC2C(=O)NC4=C(C=CC(=C4)C(F)(F)F)C(F)(F)F)CCC5C3(CCC(=O)N5)C |