For research use only. Not for therapeutic Use.
Dihydrobaicalein is a PLK1 Inhibitor with an IC50 of 6.3 μM. Dihydrobaicalein also inhibits VRK2 and PLK2. Dihydrobaicalein is a natural product that can be isolated from Scutellaria scandens[1].
| Catalog Number | I041047 |
| CAS Number | 35683-17-1 |
| Synonyms | 5,6,7-trihydroxy-2-phenyl-2,3-dihydrochromen-4-one |
| Molecular Formula | C15H12O5 |
| Purity | ≥95% |
| InChI | InChI=1S/C15H12O5/c16-9-6-11(8-4-2-1-3-5-8)20-12-7-10(17)14(18)15(19)13(9)12/h1-5,7,11,17-19H,6H2 |
| InChIKey | GPDJGLOROGNHJD-UHFFFAOYSA-N |
| SMILES | C1C(OC2=C(C1=O)C(=C(C(=C2)O)O)O)C3=CC=CC=C3 |
| Reference | [1]. Woo SU, et al. 7-O-Methylwogonin from Scutellaria baicalensis Disturbs Mitotic Progression by Inhibiting Plk1 Activity in Hep3B Cells. Planta Med. 2019 Feb;85(3):217-224. |
