Dihydrocaffeic Acid

• CAT Number: R057929
• CAS Number: 1078-61-1
• Molecular Formula: C9H10O4
• Molecular Weight: 182.175
• Purity: ≥95%
• Synonyms: 3,4-Dihydroxy-β-phenylpropionic Acid; 3,4-Dihydroxybenzenepropionic Acid; 3,4-Dihydroxyhydrocinnamic Acid; 3,4-Dihydroxyphenylpropionic Acid; 3-(3,4-Dihydroxyphenyl)propanoic Acid; 3-(3,4-Dihydroxyphenyl)propionic Acid; Hydrocaffeic Acid; NSC 407275
• Target: Metabolic Enzyme/Protease
• Storage: Store at -20°C
• IUPAC Name: 3-(3,4-dihydroxyphenyl)propanoic acid
• InChI: InChI=1S/C9H10O4/c10-7-3-1-6(5-8(7)11)2-4-9(12)13/h1,3,5,10-11H,2,4H2,(H,12,13)
• InChIKey: DZAUWHJDUNRCTF-UHFFFAOYSA-N
• SMILES: C1=CC(=C(C=C1CCC(=O)O)O)O

Dihydrocaffeic Acid (CAS 1078-61-1) is a natural product containing a catechol group with an α,β-unsaturated carboxylic acid chain. Dihydrocaffeic Acid has been shown to have hepatoprotective activity. Dihydrocaffeic Acid is a metabolite of Caffeic Acid with potent antioxidant properties.

Reference

1.Pérez‐Alvarez, V., R. A. Bobadilla, and P. Muriel. "Structure–hepatoprotective activity relationship of 3, 4‐dihydroxycinnamic acid (caffeic acid) derivatives." Journal of Applied Toxicology: An International Journal 21.6 (2001): 527-531.
2.Huang, Junjun, Tomas de Paulis, and James M. May. "Antioxidant effects of dihydrocaffeic acid in human EA. hy926 endothelial cells." The Journal of nutritional biochemistry 15.12 (2004): 722-729.
3.Poquet, Laure, Michael N. Clifford, and Gary Williamson. "Investigation of the metabolic fate of dihydrocaffeic acid." Biochemical pharmacology 75.5 (2008): 1218-1229.