For research use only. Not for therapeutic Use.
<span style="font-family: arial, helvetica, sans-serif; font-size: 12px; color: rgb(0, 0, 0);">dihydroergocristine (CAS 17479-19-5) <span style="orphans: 2; widows: 2;">is an ergot alkaloid</span></span><span style="font-family: arial, helvetica, sans-serif; font-size: 12px; color: rgb(0, 0, 0);"><span style="orphans: 2; widows: 2;">. Alongside dihydroergocornine</span></span><span style="font-family: arial, helvetica, sans-serif; font-size: 12px; color: rgb(0, 0, 0);"><span style="orphans: 2; widows: 2;"> and dihydroergocryptine</span></span><span style="color: rgb(0, 0, 0);"><span style="font-family: arial, helvetica, sans-serif; font-size: 12px; orphans: 2; widows: 2;">, it is one of the components of ergoloid mesylates. It </span><span style="font-variant-ligatures: normal; orphans: 2; widows: 2;"><font face="arial, helvetica, sans-serif">exercises a double agonistic/antagonistic activity on</font><font face="Arial, sans-serif" size="2"> </font></span><span style="font-family: arial, helvetica, sans-serif; font-size: 12px; font-variant-ligatures: normal; orphans: 2; widows: 2;">dopaminergic and adrenergic receptors, </span></span><span style="color:#000000;"><span style="font-family:arial,helvetica,sans-serif;"><span style="font-size:12px;"><span style="font-variant-ligatures: normal; orphans: 2; widows: 2;">mainly used for age-related cognitive </span><span style="font-variant-ligatures: normal; orphans: 2; widows: 2;">impairment.</span></span></span></span>
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| Catalog Number | M076466 |
| CAS Number | 17479-19-5 |
| Molecular Formula | C35H41N5O5 |
| Purity | ≥95% |
| Storage | -20°C |
| IUPAC Name | (6aR,9R,10aR)-N-[(1S,2S,4R,7S)-7-benzyl-2-hydroxy-5,8-dioxo-4-propan-2-yl-3-oxa-6,9-diazatricyclo[7.3.0.02,6]dodecan-4-yl]-7-methyl-6,6a,8,9,10,10a-hexahydro-4H-indolo[4,3-fg]quinoline-9-carboxamide |
| InChI | InChI=1S/C35H41N5O5/c1-20(2)34(37-31(41)23-16-25-24-11-7-12-26-30(24)22(18-36-26)17-27(25)38(3)19-23)33(43)40-28(15-21-9-5-4-6-10-21)32(42)39-14-8-13-29(39)35(40,44)45-34/h4-7,9-12,18,20,23,25,27-29,36,44H,8,13-17,19H2,1-3H3,(H,37,41)/t23-,25-,27-,28+,29+,34-,35+/m1/s1 |
| InChIKey | DEQITUUQPICUMR-HJPBWRTMSA-N |
| SMILES | CC(C)C1(C(=O)N2C(C(=O)N3CCCC3C2(O1)O)CC4=CC=CC=C4)NC(=O)C5CC6C(CC7=CNC8=CC=CC6=C78)N(C5)C |
| Reference | 1.<span style="font-family: Arial, sans-serif; font-size: 13px; font-variant-ligatures: normal; orphans: 2; widows: 2;">Coppi, G. "Dihydroergocristine. A review of pharmacology and toxicology." </span><i style="font-family: Arial, sans-serif; font-size: 13px; font-variant-ligatures: normal; orphans: 2; widows: 2;">Arzneimittel-Forschung</i><span style="font-family: Arial, sans-serif; font-size: 13px; font-variant-ligatures: normal; orphans: 2; widows: 2;"> 42.11A (1992): 1381.<br /> |
