Dihydromethysticin

• CAT Number: I002527
• CAS Number: 19902-91-1
• Molecular Formula: C15H16O5
• Molecular Weight: 276.28
• Purity: ≥95%
• Target: Cytochrome P450
• Solubility: 10 mM in DMSO
• Storage: Store at -20℃
• IUPAC Name: (2S)-2-[2-(1,3-benzodioxol-5-yl)ethyl]-4-methoxy-2,3-dihydropyran-6-one
• InChI: InChI=1S/C15H16O5/c1-17-12-7-11(20-15(16)8-12)4-2-10-3-5-13-14(6-10)19-9-18-13/h3,5-6,8,11H,2,4,7,9H2,1H3/t11-/m0/s1
• InChIKey: RSIWXFIBHXYNFM-NSHDSACASA-N
• SMILES: COC1=CC(=O)OC(C1)CCC2=CC3=C(C=C2)OCO3

Dihydromethysticin (Cat.No:I002527) is a natural compound found in the roots of the kava plant. It possesses anxiolytic and sedative properties and is traditionally used in herbal medicine for relaxation and stress relief. Dihydromethysticin acts on the central nervous system, promoting calmness and reducing anxiety.

Reference

[1]. Ma Y, et al. Desmethoxyyangonin and dihydromethysticin are two major pharmacological kavalactones with marked activity on the induction of CYP3A23. Drug Metab Dispos. 2004 Nov;32(11):1317-24.

[2]. Walden J, et al. Effects of kawain and dihydromethysticin on field potential changes in the hippocampus. Prog Neuropsychopharmacol Biol Psychiatry. 1997 May;21(4):697-706.

[3]. Sarris J, et al. Kava: a comprehensive review of efficacy, safety, and psychopharmacology. Aust N Z J Psychiatry. 2011 Jan;45(1):27-35.