Dihydroneopterin

• CAT Number: R040395
• CAS Number: 1218-98-0
• Molecular Formula: C₉H₁₃N₅O₄
• Molecular Weight: 255.23
• Purity: ≥95%
• Synonyms: 2-Amino-7,8-dihydro-6-[(1S,2R)-1,2,3-trihydroxypropyl]-4(3H)-pteridinone; D-Erythro-1-(2-amino-7,8-dihydro-4-hydroxy-6-pteridinyl)-1,2,3-propanetrio; [S-(R*,S*)]-2-Amino-7,8-dihydro-6-(1,2,3-trihydroxypropyl)-4(1H)-pteridinone; 2-Amino-7,8-dihydro-6-
• Target: Immunology/Inflammation
• Storage: -20°C
• IUPAC Name: 2-amino-6-[(1S,2R)-1,2,3-trihydroxypropyl]-7,8-dihydro-3H-pteridin-4-one
• InChI: InChI=1S/C9H13N5O4/c10-9-13-7-5(8(18)14-9)12-3(1-11-7)6(17)4(16)2-15/h4,6,15-17H,1-2H2,(H4,10,11,13,14,18)/t4-,6+/m1/s1
• InChIKey: YQIFAMYNGGOTFB-XINAWCOVSA-N
• SMILES: C1C(=NC2=C(N1)N=C(NC2=O)N)C(C(CO)O)O

7,8-Dihydroneopterin（Cat No.:R040395） is an inflammatory marker that plays a role in inducing apoptosis of astrocytes and neurons by upregulating the expression of nitric oxide synthase (iNOS). Its ability to promote iNOS expression leads to increased nitric oxide production, contributing to neuroinflammation and neurodegeneration. Due to its involvement in these processes, 7,8-Dihydroneopterin serves as a valuable tool in the study of neurodegenerative diseases, providing insights into the underlying mechanisms and potential therapeutic targets for managing these conditions.