Dihydrotetrabenazine

• CAT Number: M020143
• CAS Number: 3466-75-9
• Molecular Formula: C19H29NO3
• Molecular Weight: 319.44
• Purity: ≥95%
• Synonyms: (+)-ALPHA-DIHYDROTETRABENAZINE;2H-BENZO[A]QUINOLIZINE-2-OL, 1,3,4,6,7,11B-HEXAHYDRO-3-ISOBUTYL-9,10-DIMETHOXY-;DIHYDROTETRABENAZINE;DTBZ;2H-Benzo[a]quinolizin-2-ol, 1,3,4,6,7,11b-hexahydro-3-isobutyl-9,10-dimethoxy-;1,3,4,6,7,11b-Hexahydro-9,10-dimet
• Storage: Store at -20°C
• IUPAC Name: 9,10-dimethoxy-3-(2-methylpropyl)-2,3,4,6,7,11b-hexahydro-1H-benzo[a]quinolizin-2-ol
• InChI: InChI=1S/C19H29NO3/c1-12(2)7-14-11-20-6-5-13-8-18(22-3)19(23-4)9-15(13)16(20)10-17(14)21/h8-9,12,14,16-17,21H,5-7,10-11H2,1-4H3
• InChIKey: WEQLWGNDNRARGE-UHFFFAOYSA-N
• SMILES: CC(C)CC1CN2CCC3=CC(=C(C=C3C2CC1O)OC)OC

Dihydrotetrabenazine (Cat No.:M020143) is a chemical compound that acts as a reversible inhibitor of vesicular monoamine transporter 2 (VMAT2). It is used in the treatment of various neurological and psychiatric disorders, including Huntington’s disease and tardive dyskinesia. By inhibiting VMAT2, dihydrotetrabenazine reduces the uptake of neurotransmitters such as dopamine into synaptic vesicles, leading to a decrease in the release of these neurotransmitters. This can help alleviate symptoms associated with excessive dopamine activity, such as involuntary movements in tardive dyskinesia. Dihydrotetrabenazine plays a crucial role in managing these challenging conditions by regulating neurotransmitter levels in the brain.

Reference

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