For research use only. Not for therapeutic Use.
Diisopropyl fluorophosphate (DFP) is an organophosphate compound commonly used as an irreversible inhibitor of serine proteases, including acetylcholinesterase (AChE). It inhibits the enzyme by phosphorylating the serine residue in its active site, leading to an accumulation of acetylcholine in nerve synapses. This results in prolonged neural stimulation, which can cause symptoms of cholinergic toxicity. DFP has been used in research to study enzyme mechanisms and nerve agent activity. Due to its potent effects on the nervous system, it is also known as a chemical warfare agent and is structurally related to nerve agents like sarin.
| Catalog Number | R000088 |
| CAS Number | 55-91-4 |
| Synonyms | Phosphorofluoridic Acid Bis(1-methylethyl) Ester; Phosphorofluoridic Acid Diisopropyl Ester; Dyflos; Floropryl; Fluorodiisopropyl phosphate; Fluostigmine; Isoflurophate; Isopropyl Fluophosphate; DFP |
| Molecular Formula | C6H14FO3P |
| Purity | ≥95% |
| Storage | Store at -20°C |
| IUPAC Name | 2-[fluoro(propan-2-yloxy)phosphoryl]oxypropane |
| InChI | InChI=1S/C6H14FO3P/c1-5(2)9-11(7,8)10-6(3)4/h5-6H,1-4H3 |
| InChIKey | MUCZHBLJLSDCSD-UHFFFAOYSA-N |
| SMILES | CC(C)OP(=O)(OC(C)C)F |
