Diloxanide furoate

• CAT Number: I003374
• CAS Number: 3736-81-0
• Molecular Formula: C14H11Cl2NO4
• Molecular Weight: 328.15
• Purity: ≥95%
• Target: Parasite
• Solubility: 10 mM in DMSO
• Storage: Store at -20°C
• IUPAC Name: [4-[(2,2-dichloroacetyl)-methylamino]phenyl] furan-2-carboxylate
• InChI: InChI=1S/C14H11Cl2NO4/c1-17(13(18)12(15)16)9-4-6-10(7-5-9)21-14(19)11-3-2-8-20-11/h2-8,12H,1H3
• InChIKey: BDYYDXJSHYEDGB-UHFFFAOYSA-N
• SMILES: CN(C1=CC=C(C=C1)OC(=O)C2=CC=CO2)C(=O)C(Cl)Cl

Diloxanide furoate（Cat No.:I003374）is a prodrug used as a luminal amoebicide for the treatment of asymptomatic intestinal infections caused by Entamoeba histolytica. Once ingested, it is hydrolyzed to its active form, diloxanide, which disrupts the metabolism of the parasite in the intestinal lumen. It is particularly effective in eradicating cyst carriers, reducing the risk of transmission. Diloxanide furoate is often combined with tissue-acting agents, such as metronidazole, for comprehensive amoebiasis management. Its minimal systemic absorption ensures a favorable safety profile, making it a reliable choice in parasitic infection control.