diMal-O-CH2COOH

• CAT Number: I040758
• CAS Number: 1620837-47-9
• Molecular Formula: C13H12N2O7
• Molecular Weight: 308.24
• Purity: ≥95%
• Synonyms: 2-[1,3-bis(2,5-dioxopyrrol-1-yl)propan-2-yloxy]acetic acid
• InChI: InChI=1S/C13H12N2O7/c16-9-1-2-10(17)14(9)5-8(22-7-13(20)21)6-15-11(18)3-4-12(15)19/h1-4,8H,5-7H2,(H,20,21)
• InChIKey: JREDLPVQALHAIP-UHFFFAOYSA-N
• SMILES: C1=CC(=O)N(C1=O)CC(CN2C(=O)C=CC2=O)OCC(=O)O

diMal-O-CH₂COOH(CAT: I040758) is a versatile bifunctional crosslinker featuring two reactive maleimide (diMal) groups and a terminal carboxylic acid connected via a methoxy spacer. The maleimide groups selectively react with thiol-containing biomolecules, such as cysteine residues, enabling efficient site-specific conjugation, while the carboxylic acid allows for further modification through amide bond formation using standard coupling agents. This compound is ideal for constructing bioconjugates, including antibody-drug conjugates (ADCs), protein-protein crosslinks, and surface modifications of nanoparticles or materials. diMal-O-CH₂COOH provides precise control over molecular assembly, making it a valuable tool in chemical biology, drug delivery, and biomaterials research.