Dimethandrolone Undecanoate

For research use only. Not for therapeutic Use.

  • CAT Number: I006388
  • CAS Number: 366472-45-9
  • Molecular Formula: C31H50O3
  • Molecular Weight: 470.738
  • Purity: ≥95%
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Dimethandrolone Undecanoate, also known as DMAU, is a selective androgen receptor modulator (SARM) potentially for the treatment of male contraception. Dimethandrolone Undecanoate has both androgenic and progestational activities, properties that may maximize gonadotropin suppression. The dual androgenic and progestational activities of DMA make it a potential candidate for a single-agent male contraceptive as well as for androgen therapy in men.


Catalog Number I006388
CAS Number 366472-45-9
Synonyms

Dimethandrolone Undecanoate; DMAU;(7R,8R,9S,10R,11S,13S,14S,17S)-7,11,13-trimethyl-3-oxo-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl undecanoate

Molecular Formula C31H50O3
Purity ≥95%
Target Selective Androgen Receptor Modulator
Solubility Soluble in DMSO
Storage 0 - 4°C for short term or -20 °C for long term
Related CAS 219296-36-3     33776-88-4     849461-90-1     167078-06-0    
InChI InChI=1S/C31H50O3/c1-5-6-7-8-9-10-11-12-13-28(33)34-27-17-16-26-30-21(2)18-23-19-24(32)14-15-25(23)29(30)22(3)20-31(26,27)4/h19,21-22,25-27,29-30H,5-18,20H2,1-4H3/t21-,22+,25+,26+,27+,29-,30+,31+/m1/s1
InChIKey FVICENFBEMJOCE-RTFNQGFNSA-N
SMILES C[C@@]12[C@@H](OC(CCCCCCCCCC)=O)CC[C@@]1([H])[C@]3([H])[C@H](C)CC4=CC(CC[C@]4([H])[C@@]3([H])[C@@H](C)C2)=O
Reference
  • Comparison of the single dose pharmacokinetics, pharmacodynamics, and safety of two novel oral formulations of dimethandrolone undecanoate (DMAU): a potential oral, male contraceptive. Ayoub R, Page ST, Swerdloff RS, Liu PY, Amory JK, Leung A, Hull L, Blithe D, Christy A, Chao JH, Bremner WJ, Wang C.Andrology. 2017 Mar;5(2):278-285. doi: 10.1111/andr.12303. Epub 2016 Dec 1. PMID: 27907978
  • Single, escalating dose pharmacokinetics, safety and food effects of a new oral androgen dimethandrolone undecanoate in man: a prototype oral male hormonal contraceptive. Surampudi P, Page ST, Swerdloff RS, Nya-Ngatchou JJ, Liu PY, Amory JK, Leung A, Hull L, Blithe DL, Woo J, Bremner WJ, Wang C.Andrology. 2014 Jul;2(4):579-87. doi: 10.1111/j.2047-2927.2014.00216.x. Epub 2014 May 2. PMID: 24789057 Free PMC Article
  • Dimethandrolone undecanoate: a new potent orally active androgen with progestational activity. Attardi BJ, Hild SA, Reel JR.Endocrinology. 2006 Jun;147(6):3016-26. Epub 2006 Feb 23. PMID: 16497801

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