Dimethindene

• CAT Number: I006389
• CAS Number: 5636-83-9
• Molecular Formula: C20H24N2
• Molecular Weight: 292.43
• Purity: ≥95%
• Synonyms: Z 2001; Z2001; Z-2001; Dimethindene; Dimetindene; Dimetindeno;N,N-dimethyl-2-(3-(1-(pyridin-2-yl)ethyl)-1H-inden-2-yl)ethanamine
• Target: Immunology/Inflammation
• Solubility: Soluble in DMSO, not in water
• Storage: 0 - 4°C for short term or -20 °C for long term
• IUPAC Name: N,N-dimethyl-2-[3-(1-pyridin-2-ylethyl)-1H-inden-2-yl]ethanamine
• InChI: InChI=1S/C20H24N2/c1-15(19-10-6-7-12-21-19)20-17(11-13-22(2)3)14-16-8-4-5-9-18(16)20/h4-10,12,15H,11,13-14H2,1-3H3
• InChIKey: MVMQESMQSYOVGV-UHFFFAOYSA-N
• SMILES: CC(C1=CC=CC=N1)C2=C(CC3=CC=CC=C32)CCN(C)C

Dimethindene(CAT: I006389) is a first-generation antihistamine that selectively antagonizes H1 histamine receptors. It is widely used in pharmacological and dermatological research to study allergic reactions and histamine-mediated inflammatory responses. Dimethindene is effective in alleviating symptoms such as itching, swelling, and redness associated with conditions like allergic rhinitis, urticaria, and atopic dermatitis. Additionally, it exhibits sedative properties due to its ability to cross the blood-brain barrier and interact with central H1 receptors. With high specificity and stability, Dimethindene is suitable for in vitro and in vivo studies, supporting the development of antihistamine therapies for allergic and inflammatory disorders.