Dimethyl-bisphenol A

• CAT Number: M046835
• CAS Number: 1568-83-8
• Molecular Formula: C17H20O2
• Molecular Weight: 256.34
• Purity: ≥95%
• Synonyms: 1-methoxy-4-[2-(4-methoxyphenyl)propan-2-yl]benzene
• InChI: InChI=1S/C17H20O2/c1-17(2,13-5-9-15(18-3)10-6-13)14-7-11-16(19-4)12-8-14/h5-12H,1-4H3
• InChIKey: OJYIBEYSBXIQOP-UHFFFAOYSA-N
• SMILES: CC(C)(C1=CC=C(C=C1)OC)C2=CC=C(C=C2)OC

Dimethyl-bisphenol A (DMBPA) is a potent HIF-1α inhibitor. Dimethyl-bisphenol A can decrease Vegfa mRNA expression[1].
Dimethyl-bisphenol A (DMBPA; 50 μM; 30 min) significantly inhibits Vegfa120 and Vegfa164 expression in large osteoclasts (OCs)[1].

Reference

[1]. Diana P Trebec-Reynolds, et al. VEGF-A expression in osteoclasts is regulated by NF-kappaB induction of HIF-1alpha. J Cell Biochem. 2010 May 15;110(2):343-51.
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