For research use only. Not for therapeutic Use.
Dioctanoylglycol (Ethylene glycol dicaprylate), a diacylglycerol analog, is a diacylglycerol kinase (DGK) inhibitor (Ki of 58 μM)[1].
Dioctanoylglycol (Dioctanoylethylene glycol) inhibits diacylglycerol phosphorylation in platelets (70-100% at 100 μM) leading to a longer-lived diacylglycerol signal[1].
| Catalog Number | I010219 |
| CAS Number | 627-86-1 |
| Synonyms | 2-octanoyloxyethyl octanoate |
| Molecular Formula | C18H34O4 |
| Purity | ≥95% |
| InChI | InChI=1S/C18H34O4/c1-3-5-7-9-11-13-17(19)21-15-16-22-18(20)14-12-10-8-6-4-2/h3-16H2,1-2H3 |
| InChIKey | HTNFLUQQANUSLR-UHFFFAOYSA-N |
| SMILES | CCCCCCCC(=O)OCCOC(=O)CCCCCCC |
| Reference | [1]. W R Bishop, et al. Attenuation of sn-1,2-diacylglycerol second messengers by diacylglycerol kinase. Inhibition by diacylglycerol analogs in vitro and in human platelets. J Biol Chem. 1986 May 25;261(15):6993-7000. |
