Diosmetin

• CAT Number: I003888
• CAS Number: 520-34-3
• Molecular Formula: C16H12O6
• Molecular Weight: 300.3
• Purity: ≥95%
• Synonyms: 5,7-dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-4H-chromen-4-one
• Target: CYP3A/CYP450
• Solubility: DMSO
• Storage: 3 years -20℃ powder
• IUPAC Name: 5,7-dihydroxy-2-(3-hydroxy-4-methoxyphenyl)chromen-4-one
• InChI: InChI=1S/C16H12O6/c1-21-13-3-2-8(4-10(13)18)14-7-12(20)16-11(19)5-9(17)6-15(16)22-14/h2-7,17-19H,1H3
• InChIKey: MBNGWHIJMBWFHU-UHFFFAOYSA-N
• SMILES: COC1=C(C=C(C=C1)C2=CC(=O)C3=C(C=C(C=C3O2)O)O)O

Diosmetin (Cat.No:I003888) is a natural flavonoid compound found in various plants, including citrus fruits and parsley. It possesses antioxidant, anti-inflammatory, and anticancer properties. Diosmetin has shown potential in promoting cardiovascular health, reducing oxidative stress, and inhibiting tumor growth. Further research is ongoing to explore its therapeutic applications and mechanisms of action.

Reference

[1]. Liu B, et al. Diosmetin induces apoptosis by upregulating p53 via the TGF-β signal pathway in HepG2 hepatoma cells. Mol Med Rep. 2016 Jul;14(1):159-64.

[2]. Yu G, et al. Diosmetin ameliorates the severity of cerulein-induced acute pancreatitis in mice by inhibiting the activation of the nuclear factor-κB. Int J Clin Exp Pathol. 2014 Apr 15;7(5):2133-42.