Diphenhydramine-d6 N-Oxide

• CAT Number: R051229
• CAS Number: 1346603-42-6
• Molecular Formula: C17H21NO2
• Molecular Weight: 277.39
• Purity: ≥95%
• Synonyms: 2-(Diphenylmethoxy)-N,N-(dimethyl-d6)ethanamine N-Oxide; [(Dimethyl-d6)amino]ethyl Benzhydryl Ether N-Oxide; NSC 9091-d6
• Storage: -20°C
• IUPAC Name: 2-benzhydryloxy-N,N-bis(trideuteriomethyl)ethanamine oxide
• InChI: InChI=1S/C17H21NO2/c1-18(2,19)13-14-20-17(15-9-5-3-6-10-15)16-11-7-4-8-12-16/h3-12,17H,13-14H2,1-2H3/i1D3,2D3
• InChIKey: OEQNVWKWQPTBSC-WFGJKAKNSA-N
• SMILES: [2H]C([2H])([2H])[N+](CCOC(C1=CC=CC=C1)C2=CC=CC=C2)(C([2H])([2H])[2H])[O-]

Diphenhydramine-d6 N-Oxide（Cat No.:R051229） is a deuterated form of diphenhydramine N-oxide, enhanced with six deuterium atoms, which improves its analytical performance in mass spectrometry and NMR studies. This compound is essential for pharmacokinetic and metabolic research, particularly in understanding the oxidative metabolism of diphenhydramine, a common antihistamine. It helps elucidate the role of metabolites in drug efficacy and safety, aiding in the development of safer, more effective antihistaminic therapies. Diphenhydramine-d6 N-Oxide is invaluable for researchers investigating the biotransformation and detoxification processes of diphenhydramine in clinical and toxicological settings.