diphenyl-1-pyrenylphosphine

• CAT Number: M013384
• CAS Number: 110231-30-6
• Molecular Formula: C28H19P
• Molecular Weight: 386.434
• Purity: ≥95%
• Synonyms: Diphenyl-1-pyrenylphosphine
• Target: NF-κB
• Storage: -20°C
• IUPAC Name: diphenyl(pyren-1-yl)phosphane
• InChI: InChI=1S/C28H19P/c1-3-10-23(11-4-1)29(24-12-5-2-6-13-24)26-19-17-22-15-14-20-8-7-9-21-16-18-25(26)28(22)27(20)21/h1-19H
• InChIKey: DSYGKYCYNVHCNQ-UHFFFAOYSA-N
• SMILES: C1=CC=C(C=C1)P(C2=CC=CC=C2)C3=C4C=CC5=CC=CC6=C5C4=C(C=C6)C=C3

DPPP is a probe that reacts stoichiometrically with hydroperoxides to yield the fluorescent molecule diphenyl-<wbr></wbr>1-<wbr></wbr>pyrenylphosphine oxide (DPPP-<wbr></wbr>O). Plasma levels of lipid hydroperoxides of phosphatidylcholine, phosphatidylethanolamine, triglycerides, and cholesteryl esters have been measured by HPLC with a post column detection system using DPPP. DPPP has also been used as a fluorescent probe for the detection of low density lipoprotein and cellular oxidation. Fluorescence of DPPP-<wbr></wbr>O can be monitor using excitation and emission wavelengths of 351 nm and 380 nm, respectively.