For research use only. Not for therapeutic Use.
Dipyridamole-d20 (CAS: 1189983-52-5), a premium pharmaceutical research compound designed for advanced cardiovascular and antithrombotic studies. As a deuterated analog of Dipyridamole, it offers enhanced stability and improved pharmacokinetic properties. Dipyridamole-d20 is ideal for use in pharmacological and biochemical research, providing precise and reliable data for your studies. This high-purity compound ensures consistent results, aiding in the development of novel therapies for cardiovascular diseases and thrombosis. Trusted by leading laboratories, Dipyridamole-d20 is your go-to solution for cutting-edge cardiovascular research. Unlock new possibilities in blood clot prevention and heart disease treatment with Dipyridamole-d20, where innovation meets reliability.
| Catalog Number | S000155 |
| CAS Number | 1189983-52-5 |
| Molecular Formula | C24H20D20N8O4 |
| Purity | ≥95% |
| Target | Phosphodiesterase (PDE) |
| IUPAC Name | 2-[[2-[bis(2-hydroxyethyl)amino]-4,8-bis(2,2,3,3,4,4,5,5,6,6-decadeuteriopiperidin-1-yl)pyrimido[5,4-d]pyrimidin-6-yl]-(2-hydroxyethyl)amino]ethanol |
| InChI | InChI=1S/C24H40N8O4/c33-15-11-31(12-16-34)23-26-20-19(21(27-23)29-7-3-1-4-8-29)25-24(32(13-17-35)14-18-36)28-22(20)30-9-5-2-6-10-30/h33-36H,1-18H2/i1D2,2D2,3D2,4D2,5D2,6D2,7D2,8D2,9D2,10D2 |
| InChIKey | IZEKFCXSFNUWAM-KHKAULECSA-N |
| SMILES | [2H]C1(C(C(N(C(C1([2H])[2H])([2H])[2H])C2=NC(=NC3=C2N=C(N=C3N4C(C(C(C(C4([2H])[2H])([2H])[2H])([2H])[2H])([2H])[2H])([2H])[2H])N(CCO)CCO)N(CCO)CCO)([2H])[2H])([2H])[2H])[2H] |
| Reference | [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [2]. Klabunde, R.E., Dipyridamole inhibition of adenosine metabolism in human blood. Eur J Pharmacol, 1983. 93(1-2): p. 21-6. [3]. Best, L.C., et al., Mode of action of dipyridamole on human platelets. Thromb Res, 1979. 16(3-4): p. 367-79. [4]. Aktas, B., et al., Dipyridamole enhances NO/cGMP-mediated vasodilator-stimulated phosphoprotein phosphorylation and signaling in human platelets: in vitro and in vivo/ex vivo studies. Stroke, 2003. 34(3): p. 764-9. |
