Disermolide

• CAT Number: I026297
• CAS Number: 127943-53-7
• Molecular Formula: C33H55NO8
• Molecular Weight: 593.802
• Purity: 98%
• Synonyms: Disermolide; XAA 296; XAA-296; XAA296.
• Solubility: Soluble in DMSO
• Appearance: Solid powder
• Storage: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
• IUPAC Name: 2H-Pyran-2-one, 6-(14-((aminocarbonyl)oxy)-2,6,12-trihydroxy-5,7,9,11,13,15-hexamethyl-3,8,16,18-nonadecatetraenyl)tetrahydro-4-hydroxy-3,5-dimethyl-, (3S-(3alpha,4beta,5beta,6alpha(2R*,3Z,5R*,6R*,7S*,8Z,11R*,12S*,13S*,14S*,15R*,16E)))-
• InChI: InChI=1S/C33H55NO8/c1-10-11-12-20(4)31(42-33(34)40)24(8)29(37)22(6)16-18(2)15-21(5)28(36)19(3)13-14-26(35)17-27-23(7)30(38)25(9)32(39)41-27/h10-15,19-31,35-38H,1,16-17H2,2-9H3,(H2,34,40)/b12-11+,14-13-,18-15-/t19?,20-,21+,22-,23+,24+,25-,26+,27+,28?,29+,30+,31+/m0/s1
• InChIKey: AADVCYNFEREWOS-ZKGNTLCTSA-N
• SMILES: O=C1[C@@H](C)[C@H](O)[C@H](C)[C@@H](C[C@H](O)/C=CC(C)C(O)[C@H](C)/C=C(C)C[C@H](C)[C@@H](O)[C@@H](C)[C@H](OC(N)=O)[C@@H](C)/C=C/C=C)O1

Discodermolide(CAT: I026297) is a highly potent polyketide natural product known for its remarkable microtubule-stabilizing properties, making it a significant compound in cancer research. Isolated from the marine sponge Discodermia dissoluta, Discodermolide exhibits strong antiproliferative activity by promoting microtubule assembly, which leads to cell cycle arrest and apoptosis in cancer cells. Its unique mechanism of action, distinct from other microtubule-targeting agents like taxanes, positions it as a valuable candidate for developing novel chemotherapeutic agents. Discodermolide is ideal for researchers focused on cancer biology, drug development, and the exploration of new cancer therapies, offering a robust tool for advancing oncological research.