For research use only. Not for therapeutic Use.
Dithranol(CAT: I000538), also known as anthralin, is a synthetic derivative of chrysarobin widely used in dermatological research for its antiproliferative and anti-inflammatory properties. It is particularly studied for its effectiveness in treating psoriasis by normalizing keratinocyte differentiation and reducing excessive cell proliferation. Dithranol exerts its action through oxidative stress induction and inhibition of mitochondrial respiration in hyperproliferative cells. Its use in controlled experimental setups provides insights into mechanisms of inflammatory skin disorders and potential therapeutic strategies. This compound is a valuable tool for exploring novel treatments in dermatology and understanding the pathology of hyperproliferative skin conditions.
| Catalog Number | I000538 |
| CAS Number | 1143-38-0 |
| Molecular Formula | C14H10O3 |
| Purity | ≥95% |
| Target | DNA/RNA Synthesis |
| Solubility | 10 mM in DMSO |
| Storage | -20°C |
| IUPAC Name | 1,8-dihydroxy-10H-anthracen-9-one |
| InChI | InChI=1S/C14H10O3/c15-10-5-1-3-8-7-9-4-2-6-11(16)13(9)14(17)12(8)10/h1-6,15-16H,7H2 |
| InChIKey | NUZWLKWWNNJHPT-UHFFFAOYSA-N |
| SMILES | C1C2=C(C(=CC=C2)O)C(=O)C3=C1C=CC=C3O |
