DL-Allylglycine

• CAT Number: I021795
• CAS Number: 7685-44-1
• Molecular Formula: C5H9NO2
• Molecular Weight: 115.13
• Purity: ≥95%
• Synonyms: 2-aminopent-4-enoic acid
• InChI: InChI=1S/C5H9NO2/c1-2-3-4(6)5(7)8/h2,4H,1,3,6H2,(H,7,8)
• InChIKey: WNNNWFKQCKFSDK-UHFFFAOYSA-N
• SMILES: C=CCC(C(=O)O)N

DL-Allylglycine (2-Aminopent-4-enoic acid) is a glutamate decarboxylase (GAD) inhibitor. DL-Allylglycine has convulsant activity that can be used in studies to induce epileptic seizures[1][2].

Reference

[1]. Castellano C, et al. Effects of DL-allylglycine, alone or in combination with morphine, on passive avoidance behaviour in C57BL/6 mice. Arch Int Pharmacodyn Ther. 1984 Jan;267(1):141-8.
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[2]. Meldrum BS, et al. Proconvulsant, convulsant and other actions of the D- and L-stereoisomers of allylglycine in the photosensitive baboon, Papio papio. Electroencephalogr Clin Neurophysiol. 1979 Oct;47(4):383-95.
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