DL-Homocysteine thiolactone-d4 hydrochloride

• CAT Number: M072296
• CAS Number: 1219805-31-8
• Molecular Formula: C4H4D4ClNOS
• Molecular Weight: 157.66
• Purity: ≥95%
• Synonyms: 3-amino-4,4,5,5-tetradeuteriothiolan-2-one;hydrochloride
• InChI: InChI=1S/C4H7NOS.ClH/c5-3-1-2-7-4(3)6;/h3H,1-2,5H2;1H/i1D2,2D2
• InChIKey: ZSEGSUBKDDEALH-PBCJVBLFSA-N
• SMILES: C1CSC(=O)C1N.Cl

DL-Homocysteine thiolactone-d4 hydrochloride is the deuterium labeled DL-Homocysteine thiolactone (hydrochloride). DL-Homocysteine thiolactone hydrochloride is a cyclic amino acid derivative that exhibits root-growth inhibitory activity.
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

Reference

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.
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[2]. Yoshihiko INAMORI, et al. Root-growth Inhibition by DL-Homocysteine Thiolactone and Its Related Compounds. Biosci. Biotech. Biochem., 59 (3), 523-525, 1995.