D,L-threo-Droxidopa-13C2,15N Hydrochloride

• CAT Number: R046747
• CAS Number: 1329556-63-9
• Molecular Formula: C9H12ClNO5
• Molecular Weight: 252.63
• Purity: ≥95%
• Synonyms: (βS)-rel-β,3-Dihydroxy-D-tyrosine-13C2,15N Hydrochloride; DL-threo-3-(3,4-Dihydroxyphenyl)serine-13C2,15N Hydrochloride; DL-DOPS-13C2,15N; L-Threodops-13C2,15N Hydrochloride; DL-threo-3,4-Dihydroxyphenylserine-?13C2,15N Hydrochloride; DL-threo-DOPS-1
• Storage: -20°C
• IUPAC Name: (2S,3R)-2-(15N)azanyl-3-(3,4-dihydroxyphenyl)-3-hydroxy(1,2-13C2)propanoic acid;hydrochloride
• InChI: InChI=1S/C9H11NO5.ClH/c10-7(9(14)15)8(13)4-1-2-5(11)6(12)3-4;/h1-3,7-8,11-13H,10H2,(H,14,15);1H/t7-,8+;/m0./s1/i7+1,9+1,10+1
• InChIKey: FFEWFMCABUNGJJ-OPABSIBTSA-N
• SMILES: C1=CC(=C(C=C1[C@H]([13C@@H]([13C](=O)O)[15NH2])O)O)O.Cl

D, L-threo-Droxidopa-13C2,15N Hydrochloride（Cat No.:R046747） is an isotopically labeled version of Droxidopa, enhanced with two carbon-13 atoms and one nitrogen-15 atom. This modification significantly improves its detectability and quantification in mass spectrometry, crucial for neuroscientific research and clinical studies on neurodegenerative diseases. As a synthetic amino acid, it serves as a prodrug, converting into norepinephrine to manage conditions like orthostatic hypotension. This compound’s isotopic enrichment is vital for tracing its metabolic pathways and absorption dynamics, thereby facilitating the development of more effective therapeutic interventions.