DL-Tryptophan-d8

For research use only. Not for therapeutic Use.

  • CAT Number: I043748
  • CAS Number: 1233395-85-1
  • Molecular Formula: C11H4D8N2O2
  • Molecular Weight: 212.27
  • Purity: ≥95%
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DL-Tryptophan-d8 is the deuterium labeled DL-Tryptophan. DL-Tryptophan is an endogenous metabolite.
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].


Catalog Number I043748
CAS Number 1233395-85-1
Synonyms

2-amino-2,3,3-trideuterio-3-(2,4,5,6,7-pentadeuterio-1H-indol-3-yl)propanoic acid

Molecular Formula C11H4D8N2O2
Purity ≥95%
InChI InChI=1S/C11H12N2O2/c12-9(11(14)15)5-7-6-13-10-4-2-1-3-8(7)10/h1-4,6,9,13H,5,12H2,(H,14,15)/i1D,2D,3D,4D,5D2,6D,9D
InChIKey QIVBCDIJIAJPQS-JLAWCNLZSA-N
SMILES C1=CC=C2C(=C1)C(=CN2)CC(C(=O)O)N
Reference

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.
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