For research use only. Not for therapeutic Use.
DL5050 is potent and highly selective human constitutive androstane receptor (hCAR) agonist with an EC50 value of 0.37 μM.
KEYWORDS: DL5050 | supplier | hCAR agonist | DL 5050 | DL-5050 | CAS [2259710-64-8] | Androstane | CAR | Agonist | Receptors
| Catalog Number | I026351 |
| CAS Number | 2259710-64-8 |
| Molecular Formula | C23H15Cl2N3O2 |
| Purity | ≥95% |
| IUPAC Name | (E)-N-[(3,4-dichlorophenyl)methoxy]-1-(6-naphthalen-2-ylimidazo[2,1-b][1,3]oxazol-5-yl)methanimine |
| InChI | InChI=1S/C23H15Cl2N3O2/c24-19-8-5-15(11-20(19)25)14-30-26-13-21-22(27-23-28(21)9-10-29-23)18-7-6-16-3-1-2-4-17(16)12-18/h1-13H,14H2/b26-13+ |
| SMILES | C1=CC=C2C=C(C=CC2=C1)C3=C(N4C=COC4=N3)/C=N/OCC5=CC(=C(C=C5)Cl)Cl |
| Reference | D Liang et al. DL5050, a Selective Agonist for the Human Constitutive Androstane Receptor. ACS Med Chem Lett. 2019 Jun 12;10(7):1039-1044. |
