For research use only. Not for therapeutic Use.
DLin-K-C3-DMA, a cationic lipid, can be used in the synthesis of nucleic acid-lipid particle to delivery of nucleic acid[1].
| Catalog Number | I045159 |
| CAS Number | 1217306-46-1 |
| Synonyms | 3-[2,2-bis[(9Z,12Z)-octadeca-9,12-dienyl]-1,3-dioxolan-4-yl]-N,N-dimethylpropan-1-amine |
| Molecular Formula | C44H81NO2 |
| Purity | ≥95% |
| InChI | InChI=1S/C44H81NO2/c1-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-35-39-44(46-42-43(47-44)38-37-41-45(3)4)40-36-34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-2/h13-16,19-22,43H,5-12,17-18,23-42H2,1-4H3/b15-13-,16-14-,21-19-,22-20- |
| InChIKey | HNTKPUXXCNQLFR-KWXKLSQISA-N |
| SMILES | CCCCCC=CCC=CCCCCCCCCC1(OCC(O1)CCCN(C)C)CCCCCCCCC=CCC=CCCCCC |
| Reference | [1]. Michael J. Hope, et al. Improved amino lipids and methods for the delivery of nucleic acids. WO2010042877A1. [2]. Semple SC, Akinc A, Chen J, et al. Rational design of cationic lipids for siRNA delivery. Nat Biotechnol. 2010;28(2):172-176. |
