DLinDAP

• CAT Number: I026359
• CAS Number: 1019000-51-1
• Molecular Formula: C41H73NO4
• Molecular Weight: 644.04
• Purity: 98%
• Synonyms: DLinDAP; D-LinDAP; D-Lin-DAP
• Solubility: Soluble in DMSO
• Appearance: Solid powder
• Storage: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
• IUPAC Name: [3-(dimethylamino)-2-[(9Z,12Z)-octadeca-9,12-dienoyl]oxypropyl] (9Z,12Z)-octadeca-9,12-dienoate
• InChI: InChI=1S/C41H73NO4/c1-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-35-40(43)45-38-39(37-42(3)4)46-41(44)36-34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-2/h13-16,19-22,39H,5-12,17-18,23-38H2,1-4H3/b15-13-,16-14-,21-19-,22-20-
• InChIKey: HCAJCMUKLZSPFT-KWXKLSQISA-N
• SMILES: CN(CC(COC(CCCCCCC/C=CC/C=CCCCCC)=O)OC(CCCCCCC/C=CC/C=CCCCCC)=O)C

DLinDAP(CAT: I026359) is an ionizable cationic lipid designed for efficient siRNA delivery in gene silencing applications. Its ionizable nature enables it to form stable lipid nanoparticles (LNPs) that protect siRNA during systemic delivery and facilitate endosomal escape for enhanced cellular uptake. DLinDAP is particularly significant in genetic and molecular research, where it supports the development of RNA-based therapeutics targeting specific genes. With its high biocompatibility and delivery efficiency, DLinDAP is a valuable tool for advancing studies in gene therapy, personalized medicine, and the treatment of genetic disorders.