For research use only. Not for therapeutic Use.
DMH4 is a potent and selective inhibitor of VEGFR2 with an IC50 of 0.16 µM[1].
| Catalog Number | R057465 |
| CAS Number | 515880-75-8 |
| Synonyms | 4-[2-[4-(3-phenylpyrazolo[1,5-a]pyrimidin-6-yl)phenoxy]ethyl]morpholine |
| Molecular Formula | C24H24N4O2 |
| Purity | ≥95% |
| InChI | InChI=1S/C24H24N4O2/c1-2-4-20(5-3-1)23-17-26-28-18-21(16-25-24(23)28)19-6-8-22(9-7-19)30-15-12-27-10-13-29-14-11-27/h1-9,16-18H,10-15H2 |
| InChIKey | SKZQZGSPYYHTQG-UHFFFAOYSA-N |
| SMILES | C1COCCN1CCOC2=CC=C(C=C2)C3=CN4C(=C(C=N4)C5=CC=CC=C5)N=C3 |
| Reference | [1]. Hao J, et al. In vivo structure-activity relationship study of dorsomorphin analogues identifies selective VEGF and BMP inhibitors. ACS Chem Biol. 2010 Feb 19;5(2):245-53. |
