DMTr-LNA-5MeU-3-CED-phosphoramidite

For research use only. Not for therapeutic Use.

  • CAT Number: I019512
  • CAS Number: 206055-75-6
  • Molecular Formula: C₄₁H₄₉N₄O₉P
  • Molecular Weight: 772.82
  • Purity: ≥95%
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DMTr-LNA-5MeU-3-CED-phosphoramidite is a nucleoside derivative. If you need, please feel free to contact us, we will reply you within 24 hours!


Catalog Number I019512
CAS Number 206055-75-6
Molecular Formula C₄₁H₄₉N₄O₉P
Purity ≥95%
Target Nucleoside Antimetabolite/Analog
Storage Store at -20°C
IUPAC Name 3-[[(1R,3R,4R,7S)-1-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-3-(5-methyl-2,4-dioxopyrimidin-1-yl)-2,5-dioxabicyclo[2.2.1]heptan-7-yl]oxy-[di(propan-2-yl)amino]phosphanyl]oxypropanenitrile
InChI InChI=1S/C41H49N4O9P/c1-27(2)45(28(3)4)55(52-23-11-22-42)54-36-35-38(44-24-29(5)37(46)43-39(44)47)53-40(36,25-50-35)26-51-41(30-12-9-8-10-13-30,31-14-18-33(48-6)19-15-31)32-16-20-34(49-7)21-17-32/h8-10,12-21,24,27-28,35-36,38H,11,23,25-26H2,1-7H3,(H,43,46,47)/t35-,36+,38-,40-,55?/m1/s1
InChIKey STPXOEPMLLHUDQ-ZRCIEBSPSA-N
SMILES CC1=CN(C(=O)NC1=O)C2C3C(C(O2)(CO3)COC(C4=CC=CC=C4)(C5=CC=C(C=C5)OC)C6=CC=C(C=C6)OC)OP(N(C(C)C)C(C)C)OCCC#N
Reference

[1]. Kumar P, et al. Locked nucleic acid (LNA) enhances binding affinity of triazole-linked DNA towards RNA. Chem Commun (Camb). 2017 Aug 3;53(63):8910-8913.

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