For research use only. Not for therapeutic Use.
DMU2139(CAT: I019774) is a potent and specific inhibitor of the enzyme CYP1B1 (cytochrome P450 1B1). CYP1B1 is a member of the cytochrome P450 enzyme family and is involved in the metabolism of various endogenous and exogenous compounds, including drugs and carcinogens. By inhibiting CYP1B1, DMU2139 may impact the metabolism and bioactivation of specific substrates that are metabolized by this enzyme.
Catalog Number | I019774 |
CAS Number | 1821143-80-9 |
Molecular Formula | C₁₉H₁₅NO₂ |
Purity | ≥95% |
Target | Cytochrome P450 |
Reference | [1]. Horley NJ, et al. Discovery and characterization of novel CYP1B1 inhibitors based on heterocyclic chalcones: Overcoming cisplatin resistance in CYP1B1-overexpressing lines. Eur J Med Chem. 2017 Mar 31;129:159-174. |