DNA-PK-IN-11

• CAT Number: I040158
• CAS Number: 1360628-91-6
• Molecular Formula: C23H17FN6O2
• Molecular Weight: 428.42
• Purity: ≥95%
• Synonyms: 3-fluoro-4-[7-methoxy-3-methyl-8-(1-methylpyrazol-4-yl)-2-oxoimidazo[4,5-c]quinolin-1-yl]benzonitrile
• InChI: InChI=1S/C23H17FN6O2/c1-28-12-14(10-27-28)15-7-16-18(8-21(15)32-3)26-11-20-22(16)30(23(31)29(20)2)19-5-4-13(9-25)6-17(19)24/h4-8,10-12H,1-3H3
• InChIKey: OOCGUVCGJIUQKC-UHFFFAOYSA-N
• SMILES: CN1C=C(C=N1)C2=C(C=C3C(=C2)C4=C(C=N3)N(C(=O)N4C5=C(C=C(C=C5)C#N)F)C)OC

DNA-PK-IN-11 is a DNA-PK inhibitor with an IC50 of <0.1 μM (DE102010035744A1; compound 36)[1].

Reference

[1]. Dr. Fuchss Thomas, et al. Imidazolonylchinoline. DE102010035744A1.