For research use only. Not for therapeutic Use.
DND-189, a low-pH fluorescent probe, is sensitive to neutral and low pH range. DND-189 can be used to measure the pH of acidic organelles[1][2].
| Catalog Number | I043812 |
| CAS Number | 152584-38-8 |
| Synonyms | 17-(2-morpholin-4-ylethylamino)-3,10-diazapentacyclo[10.7.1.02,10.04,9.016,20]icosa-1(20),2,4,6,8,12,14,16,18-nonaen-11-one |
| Molecular Formula | C24H22N4O2 |
| Purity | ≥95% |
| InChI | InChI=1S/C24H22N4O2/c29-24-18-5-3-4-16-19(25-10-11-27-12-14-30-15-13-27)9-8-17(22(16)18)23-26-20-6-1-2-7-21(20)28(23)24/h1-9,25H,10-15H2 |
| InChIKey | JQDZUSDVVHXANW-UHFFFAOYSA-N |
| SMILES | C1COCCN1CCNC2=C3C=CC=C4C3=C(C=C2)C5=NC6=CC=CC=C6N5C4=O |
| Reference | [1]. Lin HJ, et, al. Fluorescence lifetime characterization of novel low-pH probes. Anal Biochem. 2001 Jul 15;294(2):118-25. [2]. Leemans B, et, al. pH-dependent effects of procaine on equine gamete activation. Biol Reprod. 2019 Nov 21;101(5):1056-1074. |
