Dodecaethylene glycol

• CAT Number: I016574
• CAS Number: 6790-09-6
• Molecular Formula: C₂₄H₅₀O₁₃
• Molecular Weight: 546.65
• Purity: ≥95%

Dodecaethylene glycol(CAT: I016574) is a PEG-based linker commonly utilized in the synthesis of PROTACs (PROteolysis TArgeting Chimeras), a cutting-edge strategy in drug development. With its polyethylene glycol (PEG) backbone, Dodecaethylene glycol serves as an integral component, facilitating the connection between a target protein-ligand and an E3 ligase recruiting ligand.

Reference

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562