Dolutegravir Sodium

• CAT Number: A000046
• CAS Number: 1051375-19-9
• Molecular Formula: C20H18F2N3NaO5
• Molecular Weight: 441.36
• Purity: ≥95%
• Synonyms: GSK-1349572A
• Target: Anti-infection
• Solubility: Soluble in DMSO
• Storage: Store at -20°C
• IUPAC Name: sodium;(3S,7R)-13-[(2,4-difluorophenyl)methylcarbamoyl]-7-methyl-9,12-dioxo-4-oxa-1,8-diazatricyclo[8.4.0.03,8]tetradeca-10,13-dien-11-olate
• InChI: InChI=1S/C20H19F2N3O5.Na/c1-10-4-5-30-15-9-24-8-13(17(26)18(27)16(24)20(29)25(10)15)19(28)23-7-11-2-3-12(21)6-14(11)22;/h2-3,6,8,10,15,27H,4-5,7,9H2,1H3,(H,23,28);/q;+1/p-1/t10-,15+;/m1./s1
• InChIKey: UGWJRRXTMKRYNK-VSLILLSYSA-M
• SMILES: C[C@@H]1CCO[C@@H]2N1C(=O)C3=C(C(=O)C(=CN3C2)C(=O)NCC4=C(C=C(C=C4)F)F)[O-].[Na+]

Dolutegravir Sodium（Cat No.:A000046）is a potent integrase strand transfer inhibitor (INSTI) essential for HIV research and antiviral therapy development. By blocking the HIV integrase enzyme, it prevents viral DNA integration into the host genome, a crucial step in viral replication. This high-purity compound is widely used in studies focusing on antiretroviral resistance, treatment efficacy, and HIV management strategies. With reliable stability and precision, Dolutegravir Sodium supports innovative research in developing effective antiviral therapies, contributing to advancements in HIV treatment and improving patient care outcomes.