For research use only. Not for therapeutic Use.
Domperidone（Cat No.:A000199）is a dopamine antagonist used primarily to relieve nausea and vomiting, improve gastrointestinal motility, and treat symptoms of gastroparesis. It works by blocking dopamine receptors in the gut and the chemoreceptor trigger zone, enhancing gastric emptying and intestinal transit. Domperidone is also utilized to increase lactation by stimulating prolactin release. Its effectiveness in managing gastrointestinal disorders and its additional benefit for lactating mothers make Domperidone a versatile medication in both gastroenterology and maternal health.
| Catalog Number | A000199 |
| CAS Number | 57808-66-9 |
| Synonyms | NA |
| Molecular Formula | C22H24ClN5O2 |
| Purity | ≥95% |
| Target | Neuronal Signaling |
| Solubility | Soluble in DMSO > 10 mM |
| Storage | -20°C |
| IUPAC Name | 6-chloro-3-[1-[3-(2-oxo-3H-benzimidazol-1-yl)propyl]piperidin-4-yl]-1H-benzimidazol-2-one |
| InChI | InChI=1S/C22H24ClN5O2/c23-15-6-7-20-18(14-15)25-22(30)28(20)16-8-12-26(13-9-16)10-3-11-27-19-5-2-1-4-17(19)24-21(27)29/h1-2,4-7,14,16H,3,8-13H2,(H,24,29)(H,25,30) |
| InChIKey | FGXWKSZFVQUSTL-UHFFFAOYSA-N |
| SMILES | C1CN(CCC1N2C3=C(C=C(C=C3)Cl)NC2=O)CCCN4C5=CC=CC=C5NC4=O |
