For research use only. Not for therapeutic Use.
DONAXINE iodomethylate(cas 5457-31-8) is an analeptic of CNS and a tocolytic Indole alkaloidDerived from the basic alkaloid Donaxine (gramine) extracted from Arundo donax (Gramineae fam.)<br />
It acts on certain subtype of 5HT receptors, is an analeptic of CNS and a tocolytic.<br />
Field of use as a new chemical and pharmacological class of analeptics and tocolytics.<br />
Recommended doses: 0.3-2.0 mg/kg (i.v.)<br />
Recommended concentrations: 3.10<sup>-6</sup> – 2.10<sup>-5</sup> g/ml
| Catalog Number | M144070 |
| CAS Number | 5457-31-8 |
| Synonyms | 3-(Dimethylaminomethyl) indole iodmethylate |
| Molecular Formula | C12H17IN2 |
| Purity | ≥95% |
| Solubility | In ethanol and methanol |
| Storage | Store in a dry, cool and dark place |
| IUPAC Name | 1H-indol-3-ylmethyl(trimethyl)azanium;iodide |
| InChI | InChI=1S/C12H17N2.HI/c1-14(2,3)9-10-8-13-12-7-5-4-6-11(10)12;/h4-8,13H,9H2,1-3H3;1H/q+1;/p-1 |
| InChIKey | STGYYGWMNTXYAJ-UHFFFAOYSA-M |
| SMILES | C[N+](C)(C)CC1=CNC2=CC=CC=C21.[I-] |
| Reference | – Yu.R.Mirzayev et al., /Arundo donax plant as a potential source of serotoninergic compounds/ at the 5-th International Symposium on the Chemistry of Natural Compounds. May 20 ~ 23 , 2003, Tashkent, Uzbekistan, p. 65<br /> |
