Donepezil HCl

• CAT Number: A000207
• CAS Number: 120011-70-3
• Molecular Formula: C24H30ClNO3
• Molecular Weight: 415.95
• Purity: ≥95%
• Target: Cholinesterase (ChE)
• Solubility: Limited solubility
• Storage: 3 years -20C powder
• IUPAC Name: 2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxy-2,3-dihydroinden-1-one;hydrochloride
• InChI: InChI=1S/C24H29NO3.ClH/c1-27-22-14-19-13-20(24(26)21(19)15-23(22)28-2)12-17-8-10-25(11-9-17)16-18-6-4-3-5-7-18;/h3-7,14-15,17,20H,8-13,16H2,1-2H3;1H
• InChIKey: XWAIAVWHZJNZQQ-UHFFFAOYSA-N
• SMILES: COC1=C(C=C2C(=C1)CC(C2=O)CC3CCN(CC3)CC4=CC=CC=C4)OC.Cl

Donepezil HCl（Cat No.:A000207）is a cholinesterase inhibitor primarily used to treat symptoms of Alzheimer’s disease. It works by inhibiting acetylcholinesterase, an enzyme that breaks down acetylcholine, thus increasing the levels of this neurotransmitter in the brain. Higher acetylcholine levels improve communication between nerve cells, helping to alleviate cognitive symptoms such as memory loss and confusion. Donepezil is commonly prescribed to manage mild to moderate Alzheimer’s but may also benefit severe cases. It is well-tolerated, with side effects typically including nausea, insomnia, and diarrhea, making it a key medication in dementia care.