Dooku1

For research use only. Not for therapeutic Use.

  • CAT Number: I018098
  • CAS Number: 2253744-54-4
  • Molecular Formula: C₁₃H₉Cl₂N₃OS
  • Molecular Weight: 326.20
  • Purity: ≥95%
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Dooku1(Cat No.:I018098)is a small molecule inhibitor that selectively targets the DUSP1 (dual specificity phosphatase 1) enzyme, which plays a key role in regulating inflammatory and stress responses in cells. By inhibiting DUSP1, Dooku1 has shown potential in modulating immune responses and reducing inflammation, making it a promising candidate for the treatment of inflammatory diseases, autoimmune disorders, and cancer. Research is still ongoing to understand its full pharmacological potential and mechanisms of action. If successful, Dooku1 could offer a new therapeutic approach to managing diseases linked to dysregulated immune signaling.


Catalog Number I018098
CAS Number 2253744-54-4
Molecular Formula C₁₃H₉Cl₂N₃OS
Purity ≥95%
Target Piezo Channel
IUPAC Name 2-[(2,6-dichlorophenyl)methylsulfanyl]-5-(1H-pyrrol-2-yl)-1,3,4-oxadiazole
InChI InChI=1S/C13H9Cl2N3OS/c14-9-3-1-4-10(15)8(9)7-20-13-18-17-12(19-13)11-5-2-6-16-11/h1-6,16H,7H2
InChIKey MNPOBXLPCWFONX-UHFFFAOYSA-N
SMILES C1=CC(=C(C(=C1)Cl)CSC2=NN=C(O2)C3=CC=CN3)Cl
Reference

[1]. Evans EL, et al. Yoda1 analogue (Dooku1) which antagonizes Yoda1-evoked activation of Piezo1 and aortic relaxation. Br J Pharmacol. 2018 May;175(10):1744-1759.

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