For research use only. Not for therapeutic Use.
DOPE-GA can be used for formulation of liposome, and used in the research of drug delivery[1].
| Catalog Number | I041735 |
| CAS Number | 228706-30-7 |
| Synonyms | 5-[2-[[(2R)-2,3-bis[[(Z)-octadec-9-enoyl]oxy]propoxy]-hydroxyphosphoryl]oxyethylamino]-5-oxopentanoic acid |
| Molecular Formula | C46H84NO11P |
| Purity | ≥95% |
| InChI | InChI=1S/C46H84NO11P/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-36-45(51)55-40-42(41-57-59(53,54)56-39-38-47-43(48)34-33-35-44(49)50)58-46(52)37-32-30-28-26-24-22-20-18-16-14-12-10-8-6-4-2/h17-20,42H,3-16,21-41H2,1-2H3,(H,47,48)(H,49,50)(H,53,54)/b19-17-,20-18-/t42-/m1/s1 |
| InChIKey | CSYWTOSHKUIHLT-PLQHGIRQSA-N |
| SMILES | CCCCCCCCC=CCCCCCCCC(=O)OCC(COP(=O)(O)OCCNC(=O)CCCC(=O)O)OC(=O)CCCCCCCC=CCCCCCCCC |
| Reference | [1]. Cuvillier O, et al. Liposomal ET-18-OCH(3) induces cytochrome c-mediated apoptosis independently of CD95 (APO-1/Fas) signaling. Blood. 1999 Nov 15;94(10):3583-92. [2]. Perkins WR, et al. Novel therapeutic nano-particles (lipocores): trapping poorly water soluble compounds. Int J Pharm. 2000 Apr 25;200(1):27-39. |
