Doripenem Hydrate

• CAT Number: A000566
• CAS Number: 364622-82-2
• Molecular Formula: C15H24N4O6S2.H2O
• Molecular Weight: 438.52
• Purity: ≥95%
• Synonyms: -4661
• Target: Antibiotic
• Solubility: >11mg/mL in DMSO
• Storage: 3 years -20C powder
• IUPAC Name: (4R,5S,6S)-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-3-[(3S,5S)-5-[(sulfamoylamino)methyl]pyrrolidin-3-yl]sulfanyl-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid;hydrate
• InChI: InChI=1S/C15H24N4O6S2.H2O/c1-6-11-10(7(2)20)14(21)19(11)12(15(22)23)13(6)26-9-3-8(17-5-9)4-18-27(16,24)25;/h6-11,17-18,20H,3-5H2,1-2H3,(H,22,23)(H2,16,24,25);1H2/t6-,7-,8+,9+,10-,11-;/m1./s1
• InChIKey: NTUBEBXBDGKBTJ-WGLOMNHJSA-N
• SMILES: C[C@@H]1[C@@H]2[C@H](C(=O)N2C(=C1S[C@H]3C[C@H](NC3)CNS(=O)(=O)N)C(=O)O)[C@@H](C)O.O

Doripenem Hydrate（Cat No.:A000566）is a broad-spectrum β-lactam antibiotic, part of the carbapenem class, used to treat a variety of bacterial infections, including those caused by multi-drug resistant organisms. It works by inhibiting bacterial cell wall synthesis, leading to bacterial cell death. Doripenem is effective against a range of Gram-positive and Gram-negative pathogens, including Pseudomonas aeruginosa. Its hydrate form enhances stability and solubility, making it suitable for intravenous administration. Doripenem Hydrate is primarily used in hospitals for severe infections, including complicated urinary tract infections and intra-abdominal infections.