DOTATATE

For research use only. Not for therapeutic Use.

  • CAT Number: I045671
  • CAS Number: 177943-88-3
  • Molecular Formula: C65H90N14O19S2
  • Molecular Weight: 1435.62
  • Purity: ≥95%
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DOTATATE is a DOTA-conjugated peptide. DOTATATE can be labelled with radionuclides for positron emission tomography (PET) imaging and peptide receptor radionuclide research (PRRT)[1][2][3][4].
177Lu-DOTATATE shows excellent antitumor effects in rats[1].


Catalog Number I045671
CAS Number 177943-88-3
Molecular Formula C65H90N14O19S2
Purity ≥95%
Reference

[1]. Jong M, et, al. Combination radionuclide therapy using 177Lu- and 90Y-labeled somatostatin analogs. J Nucl Med. 2005 Jan;46 Suppl 1:13S-7S.
 [Content Brief]

[2]. Gains JE, et, al. 68Ga-DOTATATE and 123I-mIBG as imaging biomarkers of disease localisation in metastatic neuroblastoma: implications for molecular radiotherapy. Nucl Med Commun. 2020 Aug 10.
 [Content Brief]

[3]. Breeman WAP, et, al. Optimising conditions for radiolabelling of DOTA-peptides with 90Y, 111In and 177Lu at high specific activities. Eur J Nucl Med Mol Imaging. 2003 Jun;30(6):917-20.
 [Content Brief]

[4]. Reubi JC, et, al. Affinity profiles for human somatostatin receptor subtypes SST1-SST5 of somatostatin radiotracers selected for scintigraphic and radiotherapeutic use. Eur J Nucl Med. 2000 Mar;27(3):273-82.
 [Content Brief]

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