Dovitinib-RIBOTAC TFA

• CAT Number: I041316
• CAS Number: 2759351-69-2
• Molecular Formula: C53H57F4N9O12S
• Molecular Weight: 1120.13
• Purity: ≥95%
• Synonyms: ethyl (5Z)-5-[[4-[2-[2-[2-[2-[2-[4-[2-(4-amino-5-fluoro-2-oxo-1H-quinolin-3-yl)-3H-benzimidazol-5-yl]piperazin-1-yl]ethylcarbamoylamino]ethoxy]ethoxy]ethoxy]ethoxy]-3-hydroxyphenyl]methylidene]-4-hydroxy-2-phenyliminothiophene-3-carboxylate;2,2,2-trifluoroacetic acid
• InChI: InChI=1S/C51H56FN9O10S.C2HF3O2/c1-2-70-50(65)44-46(63)41(72-49(44)56-33-7-4-3-5-8-33)30-32-11-14-40(39(62)29-32)71-28-27-69-26-25-68-24-23-67-22-16-55-51(66)54-15-17-60-18-20-61(21-19-60)34-12-13-36-38(31-34)58-47(57-36)43-45(53)42-35(52)9-6-10-37(42)59-48(43)64;3-2(4,5)1(6)7/h3-14,29-31,62-63H,2,15-28H2,1H3,(H,57,58)(H3,53,59,64)(H2,54,55,66);(H,6,7)/b41-30-,56-49?
• InChIKey: SSLPJCLVPXUGSX-GLWXAOSUSA-N
• SMILES: CCOC(=O)C1=C(/C(=C/C2=CC(=C(C=C2)OCCOCCOCCOCCNC(=O)NCCN3CCN(CC3)C4=CC5=C(C=C4)N=C(N5)C6=C(C7=C(C=CC=C7F)NC6=O)N)O)/SC1=NC8=CC=CC=C8)O.C(=O)(C(F)(F)F)O

Dovitinib-RIBOTAC TFA（Cat No.:I041316）is a targeted therapeutic agent combining the tyrosine kinase inhibitor dovitinib with a RIBOTAC (RNA-targeted small molecule) technology. Dovitinib is known for its ability to inhibit multiple kinases involved in cancer cell signaling, while the RIBOTAC technology enhances selective targeting of specific RNA sequences in cancer cells, thereby disrupting their gene expression. The combination of these two mechanisms aims to improve the precision and effectiveness of cancer treatment by not only inhibiting tumor growth but also modulating RNA pathways. This dual-action approach has shown potential for treating various cancers in preclinical studies.