Doxapram Hydrochloride Hydrate

• CAT Number: A000472
• CAS Number: 7081-53-0
• Molecular Formula: C24H30N2O2.HCl.H2O
• Molecular Weight: 432.98
• Purity: ≥95%
• Target: Potassium Channel
• Storage: Room Temperature
• IUPAC Name: 1-ethyl-4-(2-morpholin-4-ylethyl)-3,3-diphenylpyrrolidin-2-one;hydrate;hydrochloride
• InChI: InChI=1S/C24H30N2O2.ClH.H2O/c1-2-26-19-22(13-14-25-15-17-28-18-16-25)24(23(26)27,20-9-5-3-6-10-20)21-11-7-4-8-12-21;;/h3-12,22H,2,13-19H2,1H3;1H;1H2
• InChIKey: ZOMBFZRWMLIDPX-UHFFFAOYSA-N
• SMILES: C1(=O)C(C(CN1CC)CCN1CCOCC1)(c1ccccc1)c1ccccc1.Cl.O

Doxapram Hydrochloride Hydrate（Cat No.:A000472）, is a pharmaceutical compound used primarily as a respiratory stimulant. This medication is administered to stimulate breathing in patients experiencing respiratory depression or inadequate ventilation, often resulting from conditions like anesthesia, drug overdose, or certain medical procedures. It works by stimulating the respiratory centers in the brain, increasing the rate and depth of breathing. Doxapram Hydrochloride Hydrate is available in various forms, including injections and oral formulations, and is used in clinical settings to help maintain adequate oxygen levels in critically ill patients.

Reference

1. Nihon Yakurigaku Zasshi. 1974 Nov;70(6):757-66.[Effect of 1-ethyl-4-(2-morpholinoethyl)-3, 3-diphenyl-2-pyrrolidinone hydrochloride hydrate (doxapram) on respiration and circulation].Kubota T, Sasaki T, Nakazawa M.