Doxazosin HCl

• CAT Number: I026482
• CAS Number: 70918-01-3
• Molecular Formula: C23H26ClN5O5
• Molecular Weight: 487.94
• Purity: 98%
• Synonyms: Doxazosin HCl; Doxazosin hydrochloride
• Solubility: To be determined
• Appearance: Solid powder
• Storage: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
• IUPAC Name: [4-(4-amino-6,7-dimethoxyquinazolin-2-yl)piperazin-1-yl]-(2,3-dihydro-1,4-benzodioxin-3-yl)methanone;hydrochloride
• InChI: InChI=1S/C23H25N5O5.ClH/c1-30-18-11-14-15(12-19(18)31-2)25-23(26-21(14)24)28-9-7-27(8-10-28)22(29)20-13-32-16-5-3-4-6-17(16)33-20;/h3-6,11-12,20H,7-10,13H2,1-2H3,(H2,24,25,26);1H
• InChIKey: AQAZIYFEPYHLHC-UHFFFAOYSA-N
• SMILES: COC1=C(C=C2C(=C1)C(=NC(=N2)N3CCN(CC3)C(=O)C4COC5=CC=CC=C5O4)N)OC.Cl

Doxazosin hydrochloride (Cat No.:I026482) is an alpha-1 adrenergic antagonist used primarily in the treatment of hypertension and symptoms of benign prostatic hyperplasia (BPH). By blocking alpha-1 receptors in vascular smooth muscle, doxazosin causes vasodilation, lowering blood pressure. In BPH, it relaxes smooth muscle in the prostate and bladder neck, improving urinary flow and reducing symptoms like frequent urination and difficulty urinating. Doxazosin is typically administered orally and can be used alone or in combination with other antihypertensive medications. It is known for its long duration of action and effectiveness in managing both conditions.