For research use only. Not for therapeutic Use.
Doxazosin Mesylate(Cat No.:A000375)is an alpha-1 adrenergic receptor antagonist used primarily to treat hypertension and benign prostatic hyperplasia (BPH). By blocking alpha-1 receptors, it causes the relaxation of blood vessels, leading to lower blood pressure, and relaxes smooth muscle in the bladder and prostate, improving urinary flow in men with BPH. Doxazosin Mesylate is well-regarded for its dual-action in managing both cardiovascular and urinary symptoms. It is typically prescribed as part of long-term treatment regimens for patients seeking blood pressure control and relief from BPH-related symptoms.
Catalog Number | A000375 |
CAS Number | 77883-43-3 |
Synonyms | NA |
Molecular Formula | C23H25N5O5 • CH3SO3H |
Purity | ≥95% |
Target | Neuronal Signaling |
Solubility | Soluble in DMSO > 10 mM |
Storage | 3 years -20C powder |
IUPAC Name | [4-(4-amino-6,7-dimethoxyquinazolin-2-yl)piperazin-1-yl]-(2,3-dihydro-1,4-benzodioxin-3-yl)methanone;methanesulfonic acid |
InChI | InChI=1S/C23H25N5O5.CH4O3S/c1-30-18-11-14-15(12-19(18)31-2)25-23(26-21(14)24)28-9-7-27(8-10-28)22(29)20-13-32-16-5-3-4-6-17(16)33-20;1-5(2,3)4/h3-6,11-12,20H,7-10,13H2,1-2H3,(H2,24,25,26);1H3,(H,2,3,4) |
InChIKey | VJECBOKJABCYMF-UHFFFAOYSA-N |
SMILES | COC1=C(C=C2C(=C1)C(=NC(=N2)N3CCN(CC3)C(=O)C4COC5=CC=CC=C5O4)N)OC.CS(=O)(=O)O |