Doxofylline

• CAT Number: A000626
• CAS Number: 69975-86-6
• Molecular Formula: C11H14N4O4
• Molecular Weight: 266.3
• Purity: ≥95%
• Synonyms: Doxophylline; 69975-86-6; Ansimar; Dioxyfilline; Ventax
• Target: Metabolic Enzyme/Protease
• Storage: -20°C
• InChI: 1S/C11H14N4O4/c1-13-9-8(10(16)14(2)11(13)17)15(6-12-9)5-7-18-3-4-19-7/h6-7H,3-5H2,1-2H3
• InChIKey: HWXIGFIVGWUZAO-UHFFFAOYSA-N
• SMILES: CN1C2=C(C(=O)N(C1=O)C)N(C=N2)CC3OCCO3

Doxofylline (Cat. No: A000626), also known as Ansimar and ABC-12-3, is a novel xanthine bronchodilator. Doxofylline’s mechanism of action is related to the inhibition of phosphodiesterase activities, but it appears to have decreased affinities towards adenosine A1 and A2 receptors, which may account for its better safety profile.

Reference

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